It would seem that the only perceptibly important change in the Pakistan's ODI squad for Ireland would be the change of guard.

Pakistan will take on Ireland in two ODIs on the 28th and the 30th of May and it will be done under a different ODI captain. Shahid Afridi has been stripped of the captaincy for this tour, leaving the Pakistan Cricket Board to name Misbah ul Haq as the Pakistan ODI captain in addition to being the Test captain.
While the captaincy future remains a question after the Pakistan Ireland ODIs, the squad picked for the Ireland tour will be expected to yield better results than the 3-2 results against the West Indies. Misbah ul Haq will have the resources of Shahid Afridi, albeit only as an all rounder.
Younis Khan finds himself in the list that leans more towards the future of Pakistan than those occupying the senior roles, making it an interesting proposition for one of the younger ones to shine to make a potential case for becoming the future captain of Pakistan in the ODI format, although given the air of uncertainty about Pakistan cricket, they must consider every opportunity a blessing.
Pakistan's ODI squad for Ireland:
Misbah-ul-Haq (capt), Younis Khan, Taufeeq Umar, Mohammad Hafeez, Asad Shafiq, Azhar Ali, Shahid Afridi, Mohammad Salman (wk), Saeed Ajmal, Abdur Rehman, Umar Akmal, Umar Gul, Wahab Riaz, Tanvir Ahmed, Junaid Khan, Hammad Azam

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